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Zoloft, prescribed generically as sertraline, is commonly used to treat panic disorders, anxiety disorders, depression, obsessive-compulsive disorders, posttraumatic stress disorder, and premenstrual dysphoric disorder. Zoloft is an antidepressant known as an SSRI or selective inhibitors of serotonin reuptake. Zoloft is not suitable for all. A complete medical history should be assessed before prescribing this drug. Patients with a medical history that includes bipolar disorders, liver disease, kidney disease, seizures, epilepsy or a history of drug abuse may not be able to take Zoloft or may require careful monitoring during therapy with the drug Zoloft, depending on the condition and the severity of the condition. The Food and Drug Administration rated this medication as a pregnancy risk category C Zoloft has been shown to cause harm and birth defects in newborn infants exposed to Zoloft, while in the uterus, particularly affecting the heart and lungs. Zoloft passes through the mother's breast milk and may harm a nursing baby. The prescribing physician should avoid prescribing this drug to pregnant or nursing, or is likely to become pregnant. There is a risk of side effects associated with Zoloft, some of which are severe. A patient experiencing a serious side effect or an allergic reaction should seek emergency medical attention. An allergic reaction will present with symptoms that include facial swelling, including swelling of the lips, mouth, tongue or throat, hives and difficulty breathing. Other serious side effects requiring emergency medical intervention include symptoms such as seizures or convulsions, tremors, chills, muscle stiffness or muscle spasms, loss of balance or coordination, agitation, confusion, excessive sweating, fast or irregular heartbeat. Some patients experience a worsening of symptoms while taking Zoloft. Patients who experience symptoms such as aggression, anxiety, agitation, irritability, mania, difficulty sleeping, anxiety attacks, panic, mood swings, self-harm or thoughts of suicide should be taken to the nearest emergency room. Other less serious side effects usually do not require emergency medical attention but should be reported to the prescribing physician. Patients should be encouraged to report all side effects. Less serious side effects are symptoms such as drowsiness, dizziness, weakness, nervousness, insomnia, agitation, dry mouth, nausea, diarrhea, changes in appetite, changes in weight or sexual dysfunction. Less serious side effects can often be reduced to a tolerable level by reducing the dose of Zoloft. Zoloft should be taken exactly as prescribed by the physician. If patients miss a dose, the dose should be taken as soon as you have in mind. However, if it is almost time for your next dose, missed dose should be omitted to avoid the possibility of an overdose. The patient should not take a double dose of this medication. An overdose present with symptoms such as dizziness, drowsiness, nausea, vomiting, palpitations, agitation, tremors, confusion, convulsions, coma or death. There is a risk of negative drug interactions associated with Zoloft. A complete medical history must be understood before prescribing this drug. Patients should be encouraged to consult with your doctor before taking any prescription of new drugs, including prescription medicines and herbal remedies. Medications known to interact with Zoloft include tramadol, digitoxin, phenytoin, lithium, anticoagulants, almotriptan, medicines for heart rhythm, and additional antidepressants. Pimozide and MAO inhibitors can lead to serious adverse interactions when taken with Zoloft, including coma or death. A patient should wait at least 14 days before starting Zoloft taken an MAO inhibitor. Molecular Formula Zoloft is C17H17Cl2N • IUPAC chemical name is 4 - (3,4-dichlorophenyl)-N-methyl-tetralin-1-amine • 306.229 molecular weight g / mol • Zoloft available: concentrate 20mg/ml 60ml bottle, tablets 25 mg tablets 100 mg, 50 mg tablets Generic Name: Sertraline Make (s): Apo-Sertraline, Lustral, Sertraline, Sertralinum, tosylate sultamicillin Generic Name: Sertraline Make (s): Apo-Sertraline, Lustral, Sertraline, Sertralinum, tosylate sultamicillin

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